Houston hosts Colorado in a Friday night Big 12 opener with the Cougars favored by 4.5. ESPN has the 7:30 p.m. ET broadcast. Houston is 2-0 behind a stingy defense, while Colorado is 1-1 and turning to Ryan Staub at quarterback. Books list Houston around -200 on the moneyline and the total between 43.5 and 45.5. Expect a physical game that could swing on turnovers and third downs.